Papaverine Impurity 13 Hcl CAS 18813-60-0 (free base)
| CAS No. | 18813-60-0 (free base) |
| Molecular Formula | C19H19NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Papaverine Impurity 13 Hcl (CAS 18813-60-0 (free base), C19H19NO4HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H19NO4HCl, Papaverine Impurity 13 Hcl contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 361.82 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H19NO4 HCl |
| Molecular Weight | 361.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Papaverine Standards
- Papaverine-d3 Hydrochloride (CAS 113718-66-4)
- Papaverine Impurity 37 (CAS 1207386-32-0)
- Papaverine Hydrochloride - Impurity E (CAS 13074-31-2)
- Papaverine EP Impurity F (CAS 139-76-4)
- Papaverine Impurity 35 (CAS 16637-56-2)
- Papaverine Impurity 14 Hcl (CAS 18694-10-5（free base）)
- Papaverine Impurity 17 (CAS 18783-43-2)
- Papaverine Impurity 2 (CAS 18813-60-0)
Recommended Standards
- Glipizide EP Impurity E (CAS 66375-96-0)
- Cefcapene Impurity 98 (CAS CATO-C4X-182498)
- Tegoprazan impurity 52 (CAS 69829-55-6)
- 1-(Isoxazolo[5,4-b]pyridin-3-yl)ethanone (CAS 1785305-56-7)
- 4-(3-Aminophenyl)butanoic acid (CAS 161466-30-4)
- 1-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-methyl-1h-pyrazol-5-amine (CAS 1175702-76-7)
- 2,6-Dinitro-4-octan-2-ylphenol (CAS 4095-54-9)
- 5-(3,3-Dimethylbutoxy)pentane-1-sulfonyl chloride (CAS 1482368-34-2)
- Dexpanthenol Racemate (CAS 16485-10-2)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
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